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Tuesday, February 3, 2015

Anti-Vaccine Movement Causes Worst Measles Epidemic In 20 Years


Roald Dahl Lost His Daughter To Measles In 1962.Here Is Advice Letter
http://paxonbothhouses.blogspot.com/2015/02/roald-dahl-lost-his-daughter-to-measles.html

The Anti-Vaccination Epidemic Is Fueled By "Education," Wealth And Privilege
http://paxonbothhouses.blogspot.com/2014/09/the-anti-vaccination-epidemic-is-fueled.html

Jenny McCarthy: Anti-Vaccination Playboy Bunny And Poster Girl For Self-Terrorization

Anti-Vaccine Movement Causes Worst Measles Epidemic In 20 Years


Measles is now spreading outward from Disneyland in California, in the worst outbreak in years. The epidemic is fueled by growing enclaves of unvaccinated people.
The CDC reports that in just the past month, 84 people from 14 states contracted measles, a number that is certainly an under-estimate, because the CDC doesn’t record every case. California alone has 59 confirmed cases, most of them linked to an initial exposure in Disneyland. A majority of people who have gotten sick were not vaccinated.
For years, scientists (including me) have warned that the anti-vaccination movement was going to cause epidemics of disease. Two years ago I wrote that the anti-vaccine movement had caused the worst whooping cough epidemic in 70 years. And now it’s happening with measles.
Finally, though, the public seems to be pushing back. Parents are starting to wake up to the danger that the anti-vax movement represents to their children and themselves.
measles-cases-616px
What’s sad about this – tragic, really – is that we eliminated measles from the U.S. in the year 2000, thanks to the measles vaccine. As this CDC graph shows, we’ve had fewer than 100 cases every year since.
But we had 644 cases in 27 states in 2014, the most in 20 years. And 2015 is already on track to be worse. Measles may become endemic in the U.S, circulating continually, thanks to the increasing numbers of unvaccinated people. Until now, each outbreak was caused by someone traveling from abroad and bringing measles to us. The anti-vaccine movement has turned this public health victory into defeat.
Anti-vaxxers have been relentless in the efforts to spread misinformation. Despite overwhelming scientific evidence that vaccines are beneficial, they endlessly repeat a variety false claims, such as:

  • Vaccines cause autism. They don’t.
  • The preservative thimerosal in vaccines causes autism. It doesn’t.
  • Natural immunity is all you need. It isn’tMeasles infects 90% of people exposed to it unless they are vaccinated.
  • A healthy lifestyle will protect you from measles. It won’t.

  • Now, finally, some parents are pushing back. Parents and schools in California, where the epidemic began, are concerned that their children will be exposed to measles from unvaccinated children in schools. And the schools are starting to do something they should have done long ago: send the unvaccinated kids home.
    The problem arises from California’s vaccine exemption policy: although public schools require kids to be vaccinated, parents can exempt their kids simply by saying they have a personal objection to vaccination. It’s not just California: only two states, Mississippi and West Virginia, don’t allow parents to claim a philosophical or religious exemption to vaccines  And Colorado has the worst rate of vaccination, at just 82%, primarily due to parents claiming a “philosophical” exemption.
    These parents are the anti-vaxxers. Thanks to them, we now have large pockets of unvaccinated children through whom epidemics can spread further an faster than we’ve seen in decades. The CDC reports that in 2014, 79% of measles cases in the U.S. involving unvaccinated people were the result of personal belief exemptions.
    Anti-vaxxers don’t recognize the threat their behavior poses to others, especially to children whose immune systems aren’t functioning properly. CNN reported this week on the case of Rhett Krawitt, a 6-year-old California boy who has gone through 4 years of chemotherapy for childhood leukemia. His leukemia is in remission and he’s back in school, but the treatment wiped out his immunity, and he’s still not ready to get vaccinated. If Rhett gets measles, he might not survive. His father Carl wrote to school district officials to ask them to ban unvaccinated children from school.
    Krawitt expects the schools to deny his request.
    Meanwhile, the parents who refuse to vaccinate their kids aren’t budging. The New York Times reported on one mother, Crystal McDonald, who refused to vaccinate any of her four children, after “researching the issue” by reading anti-vaccine websites. When their high school sent her daughter home for two weeks, the daughter asked if she could get the measles shot so she could return. As quoted in the Times, McDonald told her daughter “I said ‘No, absolutely not.’ I said I’d rather you miss an entire semester than you get the shot.’”
    Where does this breathtaking science denialism come from? It’s been building for years, as I and many others have written. The wave began with a 1998 paper published in The Lancet by Andrew Wakefield, claiming that the MMR vaccine was linked to autism. Wakefield’s work was later shown to be fraudulent, and his claims about the vaccine “dishonest and irresponsible.” After lengthy investigations, the paper was retracted and Wakefield lost his medical license. Despite this very public repudiation, Wakefield has stuck to his claims, though, and has spent much of the past 15 years speaking (or perhaps “preaching” would be a better term) to anti-vaccine groups, to whom he is a kind of folk hero.
    It’s not just Wakefield, though. Anti-vaccine messages have been broadcast aggressively by the group Generation Rescue, led by former Playboy playmate and MTV host Jenny McCarthy, and by Age of Autism, a group dedicated to the proposition that vaccines cause autism. (Age of Autism is doing it again right now.) And just last summer, Robert F. Kennedy Jr. published a new book further promoting the long-discredited claim that thimerosal causes autism.
    Most of the anti-vax crowd have no scientific training or expertise, which might explain (but doesn’t excuse) their complete ignorance of the science. Over the past 15 years, dozens of studies involving hundreds of thousands of people have shown convincingly that neither vaccines nor any of the ingredients in them are linked to autism. Vaccines are not only safe, but they are perhaps the greatest public health success in the history of civilization.
    Measles, though, is dangerous. The CDC’s Anne Schuchat had a message for parents this week:
    I want to make sure that parents who think that measles is gone and haven’t made sure that they or their children are vaccinated are aware that measles is still around and it can be serious. And that MMR vaccine is safe and effective and highly recommended.”
    Make no mistake, measles is a very dangerous infection. In the current outbreak, 25% of victims have ended up in the hospital. And it is extremely infectious: the CDC’s Schuchat explained that:
    “You can catch it [measles] just by being in the same room as a person with measles even if that person left the room because the virus can hang around for a couple of hours.”
    Perhaps the Disneyland epidemic, which has now spread to 14 states, will finally convince parents, schools, and state legislatures that they need to insist that children get vaccinated before going to school. Perhaps it will also convince parents to stop listening to nonsense, and choose wisely by getting their children vaccinated against measles. We won this battle before, and we can win it again.

    10 comments:

    1. Measles Vaccines CAN NOT Prevent Measles Outbreaks
      by Jeff Prager

      The following essay contains excerpts from the article linked at the end of the essay.

      Between 2% and 10% of people vaccinated for Measles will get ZERO protection. The vaccine won't work because we are all genetically different.

      9% of children getting two doses of the vaccine will lose their ability to make antibodies (erroneously called "immunity") after seven and a half years. As more time passes, more people lose immunity. We have outbreaks of measles not because people are unvaccinated but because the measles vaccine does not work. I had measles as a child. I have lifetime immunity.

      According to Dr. Gregory Poland, one of the world’s most admired and most advanced thinkers in the field of vaccinology, the answer lies in our genes.

      Because of their genetic predisposition, some people will not respond to the current measles vaccine, even with additional boosters. By the same token, the genetic predisposition of others makes them susceptible to harm from the measles vaccine—neurological disorders, autism—leading to public wariness, including among the well educated. What is needed, suggests Dr. Poland, is for the public health establishment to accept that the current measles vaccine has so many drawbacks as to make it unworkable, and get on with the job of developing next-generation vaccines.

      This next generation vaccine technology, which his Mayo Clinic group is helping pioneer, marries vaccinology with genomics to create personalized, rather than one-size-fits-all vaccines, which we know cause neurological disorders.

      1. Lawrence Solomon: Vaccines Can't Prevent Measles Outbreaks, Financial Post, May 1, 2014: http://business.financialpost.com/2014/05/01/lawrence-solomon-vaccines-cant-prevent-measles-outbreaks/

      ReplyDelete
    2. Measles Outbreaks? Why?
The Measles Vaccine Causes Measles!
by Jeff Prager
      Please allow me to explain, using 10 peer reviewed studies, why we have measles outbreaks.

      In 2012 there were 33,561 deaths from car accidents [1]. There have been zero deaths from measles for the last 10 years.

      During the 1950s and 60s the USA had 3-4 million reported cases of measles per year and an average of 450 people per year died from complications related to the measles virus. In 2010 there were almost 800 bicycle accidents that resulted in death [2]. More people die each year from bicycles than measles.

      The population of the US in 1963 was 189,241,98. This means that before the vaccine was introduced the percentage of the US population that died from measles was 0.000237%. Today, the percentage of the global population that dies from measles, after vaccination has been introduced for 51 years, is 0.00328%. This means that before the vaccine was introduced less people in the USA died than die today from measles globally.

      ~ 0.000237% is less than 0.00328% ~

      Even worse, scientific evidence demonstrates that individuals vaccinated with live virus vaccines such as MMR (measles, mumps and rubella), rotavirus, chicken pox, shingles and influenza can shed the virus for many weeks or months afterwards and infect the vaccinated and unvaccinated alike [3,4,5,6,7,8,9,10,11,12,13]. This revelation, that vaccinated people shed measles virus which can infect even other vaccinated people for weeks and even months after vaccination, fully explains any current measles outbreaks.
      The image that accompanies this post, from Johns Hopkins, shows that immunocompromised persons should avoid people that have recently been vaccinated for measles, chicken pox, rubella, influenza, polio or smallpox because these vaccinated people can SHED THE VIRUS FOR WEEKS AND EVEN MONTHS infecting even people that are already vaccinated.

      References listed in the comment below:


      ReplyDelete
    3. Uncontested Published, Peer Reviewed Literature On Thimerosal and Neurological Disorders Including Autistic Spectrum Disorder:

      1. Blood Levels of Mercury Are Related to Diagnosis of Autism: A Reanalysis of an Important Data Set, Clinical Neurology, 2007: http://jcn.sagepub.com/content/22/11/1308.abstract

      2. Mercury And Autism: Accelerating Evidence, Neuro Endocrinology Letters, 2005: http://www.ncbi.nlm.nih.gov/pubmed/16264412?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=2&log%24=relatedreviews&logdbfrom=pubmed

      3. Immunological Findings In Autism, International Review of Neurobiology, 2005: http://www.ncbi.nlm.nih.gov/pubmed/16512356

      4. A two-phase study evaluating the relationship between Thimerosal-containing vaccine administration and the risk for an autism spectrum disorder diagnosis in the United States, Translational Neurodegeneration, December 2013: http://www.ncbi.nlm.nih.gov/pubmed/24354891


      7. Adverse Effects of Pertussis and Rubella Vaccines, Institute of Medicine, the National Academies Collection, 1991: http://www.ncbi.nlm.nih.gov/pubmed/25121241

      8. Immunization Safety Review: Thimerosal-Containing Vaccines and Neurodevelopmental Disorders, Executive Summary, NCBI, 2001: http://www.ncbi.nlm.nih.gov/books/NBK223721/

      9. Methodological issues and evidence of malfeasance in research purporting to show thimerosal in vaccines is safe, BioMed Research International, June 2014: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065774/#B20

      10. Increased risk of developmental neurologic impairment after high exposure to thimerosal-containing vaccine in first month of life. Proceedings of the Epidemic Intelligence Service Annual Conference; 2000; Atlanta, Ga, USA. Centers for Disease Control and Prevention, Atlanta, Ga, USA, 2000.

      ReplyDelete
    4. More Uncontested Published, Peer Reviewed Literature On Thimerosal and Neurological Disorders Including Autistic Spectrum Disorder:

      11. Effect of thimerosal on the neurodevelopment of premature rats, World Journal of Pediatrics, PubMed, NCBI, November 2013: http://www.ncbi.nlm.nih.gov/pubmed/24235069

      12. Thimerosal exposure and the role of sulfation chemistry and thiol availability in autism, International Journal of Environmental Research And Public Health, August 2013: http://www.ncbi.nlm.nih.gov/pubmed/23965928

      13. Administration of aluminium to neonatal mice in vaccine-relevant amounts is associated with adverse long term neurological outcomes, Journal Of Inorganic Biochemistry, November 2013: http://www.ncbi.nlm.nih.gov/pubmed/23932735

      14. B-lymphocytes from a population of children with autism spectrum disorder and their unaffected siblings exhibit hypersensitivity to thimerosal, Journal of Toxicology, June 2013: http://www.ncbi.nlm.nih.gov/pubmed/23843785

      15. Aluminum in the central nervous system (CNS): toxicity in humans and animals, vaccine adjuvants, and autoimmunity, Journal Immunological Research, July 2013: http://www.ncbi.nlm.nih.gov/pubmed/23609067

      16. Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA, The Journal of Toxicology, June 2012: http://www.ncbi.nlm.nih.gov/pubmed/22811707

      17. Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate, Journal Neurochemical Research, February 2012: http://www.ncbi.nlm.nih.gov/pubmed/22015977

      18. Persistent behavioral impairments and alterations of brain dopamine system after early postnatal administration of thimerosal in rats, Behavioral Brain Research, PubMed, NCBI, September 2011: http://www.ncbi.nlm.nih.gov/pubmed/21549155

      19. Lasting neuropathological changes in rat brain after intermittent neonatal administration of thimerosal, Association of Polish Neuropathologists And Medical Research Center, 2010: http://www.ncbi.nlm.nih.gov/pubmed/21225508

      20. Hepatitis B vaccination of male neonates and autism diagnosis, NHIS 1997-2002, Journal of Toxicology and Environmental Health, 2010: http://www.ncbi.nlm.nih.gov/pubmed/21058170

      21. The biological basis of autism spectrum disorders: Understanding causation and treatment by clinical geneticists, US National Library of Medicine, 2010: http://www.ncbi.nlm.nih.gov/pubmed/20628444

      ReplyDelete
    5. The Claim
      by Jeff Prager

      Since thimerosal was removed from vaccines the incidence of autism has not decreased.

      The truth:

      Since thimerosal has been removed from most vaccines (thimerosal is still used in most influenza vaccines and thimerosal is still used in 11 vaccines total [2,3]) the number of Neurological Disorders has decreased in the US.

      That's right. Since thimerosal was removed from vaccines the incidence of neurological disorders has decreased. So when people tell you that since thimerosal was removed from most vaccines that the incidence of autism and neurological disorders has not decreased you can tell them, they're wrong.

      Additionally, the handling of vaccine safety data from the National Immunization Program of the CDC has been called into question by the Institute of Medicine of the National Academy of Sciences since 2005.

      Med Sci Monit. 2006 Jun;12(6):CR231-9. Epub 2006 May 29.

      An assessment of downward trends in neurodevelopmental disorders in the United States following removal of Thimerosal from childhood vaccines.

      http://www.ncbi.nlm.nih.gov/pubmed/16733480

      ReplyDelete
    6. Pro-Lifers, Are You Also Pro-Vaccine?
      by Jeff Prager

      The 2009/2010 Influenza Season Vaccine caused 1,321 vaccine-related spontaneous abortions and stillbirths reported to the Vaccine Adverse Reaction System (VAERS) yielding an ascertainment-corrected rate of 590 fetal-loss reports per million pregnant women vaccinated (or 1 per 1695).

      http://www.ncbi.nlm.nih.gov/pubmed/23023030

      ReplyDelete
    7. Pro-Vaccine People, Why?
      by Jeff Prager

      • Why don't pro-vaccine people know about this peer reviewed report published in Clinical Vaccine Immunology and copyrighted to the American Society for Microbiology? The report states:

      "varicella [chicken pox] vaccination has not been effective in preventing varicella in South Korea"


      1. Varicella and Varicella Vaccination in South Korea, Clinical Vaccine Immunology, US National Library of Medicine National Institutes of Health, ©American Society for Microbiology, by Sung Hee Oh, et al., May 2014: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018876/

      • Why don't pro-vaccine people know about this peer reviewed report which was published in Translational Neurodegeneration, which states:

      "Routine childhood vaccination is an important public health tool to reduce the morbidity and mortality associated with infectious diseases, but the present study provides new epidemiological evidence supporting an association between increasing organic-Hg exposure from Thimerosal-containing childhood vaccines and the subsequent risk of an ASD diagnosis."

      2. A two-phase study evaluating the relationship between Thimerosal-containing vaccine administration and the risk for an autism spectrum disorder diagnosis in the United States, Translational Neurodegeneration, December 2013: http://www.ncbi.nlm.nih.gov/pubmed/24354891

      • Why don't pro-vaccine people know about or discuss this peer reviewed report which was published in 2007 by the Department of Psychology at the University of Iowa in the Journal of Child Neurology and written by Dr's M. Catherine DeSoto, PhD and Robert T. Hitlan, PhD. The report states:

      "We have reanalyzed the data set originally reported by Ip et al. in 2004 and have found that the original p value was in error and that a significant relation does exist between the blood levels of mercury and diagnosis of an autism spectrum disorder. Moreover, the hair sample analysis results offer some support for the idea that persons with autism may be less efficient and more variable at eliminating mercury from the blood."

      3. Blood Levels of Mercury Are Related to Diagnosis of Autism: A Reanalysis of an Important Data Set, Clinical Neurology, 2007: http://jcn.sagepub.com/content/22/11/1308.abstract

      • Why don't pro-vaccine people know about this peer reviewed report which was published in 2005 in Neuro Endocrinology Letters by J. Mutter, et al., which states:


      "Recently, it was found that autistic children had a higher mercury exposure during pregnancy due to maternal dental amalgam and thimerosal-containing immunoglobulin shots. It was hypothesized that children with autism have a decreased detoxification capacity due to genetic polymorphism. In vitro, mercury and thimerosal in levels found several days after vaccination inhibit methionine synthetase (MS) by 50%. Normal function of MS is crucial in biochemical steps necessary for brain development, attention and production of glutathione, an important antioxidative and detoxifying agent. Repetitive doses of thimerosal leads to neurobehavioral deteriorations in autoimmune susceptible mice, increased oxidative stress and decreased intracellular levels of glutathione in vitro. Subsequently, autistic children have significantly decreased level of reduced glutathione. Promising treatments of autism involve detoxification of mercury, and supplementation of deficient metabolites."

      4. Mercury And Autism: Accelerating Evidence, Neuro Endocrinology Letters, 2005: http://www.ncbi.nlm.nih.gov/pubmed/16264412?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=2&log%24=relatedreviews&logdbfrom=pubmed

      ReplyDelete
    8. Pro-Vaccine People, Why?
      by Jeff Prager


      • What about this 2005 peer reviewed report published by the Department of Biology, Jackson State University, Mississippi, in The International Review of Neurobiology that states, regarding Thimerosal:

      "The possibility of its involvement in autism cannot be ruled out."

      5. Immunological Findings In Autism, International Review of Neurobiology, 2005: http://www.ncbi.nlm.nih.gov/pubmed/16512356

      • Why don't pro-vaccine people know about and discuss this Extremely Important peer reviewed report published in 1991 by the Institute of Medicine (US) Committee to Review the Adverse Consequences of Pertussis and Rubella Vaccines in Washington DC. This study was published in hard-cover by the National Academies Press. You got your copy or heard about it, at least, right? This study states:

      "that the evidence is consistent with a causal relation between DPT vaccine and acute encephalopathy and shock and "unusual shock-like state," and between RA 27/3 rubella vaccine and chronic arthritis; and that the evidence indicates a causal relation between DPT vaccine and anaphylaxis, between the pertussis component of DPT vaccine and protracted, inconsolable crying, and between RA 27/3 rubella vaccine and acute arthritis."

      6. Adverse Effects of Pertussis and Rubella Vaccines, Institute of Medicine, the National Academies Collection, 1991: http://www.ncbi.nlm.nih.gov/pubmed/25121241

      • Why don't pro-vaccine people know about and discuss this peer reviewed report published just last year in June of 2014 in BioMed Research International which states:

      "There are over 165 studies that have focused on Thimerosal, an organic-mercury (Hg) based compound, used as a preservative in many childhood vaccines, and found it to be harmful … in a study conducted directly by CDC epidemiologists, a 7.6-fold increased risk of autism from exposure to Thimerosal during infancy was found … "

      8. Methodological issues and evidence of malfeasance in research purporting to show thimerosal in vaccines is safe, BioMed Research International, June 2014: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065774/#B20

      ReplyDelete
    9. Pro-Vaccine People, Why?
      by Jeff Prager


      • Why don't pro-vaccine people know about and discuss this peer reviewed report published in the Journal of Toxicology in 2013 that states:

      "Cells hypersensitive to thimerosal also had higher levels of oxidative stress markers, protein carbonyls, and oxidant generation. This suggests certain individuals with a mild mitochondrial defect may be highly susceptible to mitochondrial specific toxins like the vaccine preservative thimerosal."

      9. B-lymphocytes from a population of children with autism spectrum disorder and their unaffected siblings exhibit hypersensitivity to thimerosal, Journal of Toxicology, June 2013: http://www.ncbi.nlm.nih.gov/pubmed/23843785


      • Why don't pro-vaccine people know about and discuss this peer reviewed report published in Immunologic Research in 2013 by Neural Dynamics Research Group from the Department of Ophthalmology and Visual Sciences at the University of British Columbia which states:

      "In young children, a highly significant correlation exists between the number of pediatric aluminum-adjuvanted vaccines administered and the rate of autism spectrum disorders."

      10. Aluminum in the central nervous system (CNS): toxicity in humans and animals, vaccine adjuvants, and autoimmunity, Journal Immunological Research, July 2013: http://www.ncbi.nlm.nih.gov/pubmed/23609067

      • Why don't pro-vaccine people know about and discuss this peer reviewed report published in the Journal of Toxicology in 2012 by the Department of Neurosurgery at Methodist Hospital in Houston. The report states:

      "We find that ethylmercury not only inhibits mitochondrial respiration leading to a drop in the steady state membrane potential, but also concurrent with these phenomena increases the formation of superoxide, hydrogen peroxide, and Fenton/Haber-Weiss generated hydroxyl radical. Additionally, we find a five-fold increase in the levels of oxidant damaged mitochondrial DNA bases and increases in the levels of mtDNA nicks and blunt-ended breaks. Highly damaged mitochondria are characterized by having very low membrane potentials, increased superoxide/hydrogen peroxide production, and extensively damaged mtDNA and proteins."

      11. Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA, The Journal of Toxicology, June 2012: http://www.ncbi.nlm.nih.gov/pubmed/22811707

      Why don't pro-vaccine people discuss this report? It was published to the Journal of Toxicology and Environmental Health by members of the PhD Program in Population Health and Clinical Outcomes Research, Stony Brook University Medical Center, State University of New York at Stony Brook. The report states:


      "Findings suggest that U.S. male neonates vaccinated with the hepatitis B vaccine prior to 1999 (from vaccination record) had a threefold higher risk for parental report of autism diagnosis compared to boys not vaccinated as neonates during that same time period."

      12. Hepatitis B vaccination of male neonates and autism diagnosis, NHIS 1997-2002, Journal of Toxicology and Environmental Health, 2010: http://www.ncbi.nlm.nih.gov/pubmed/21058170


      There are 100s of 1000s of reports submitted for review every year, maybe millions. There's simply no way to keep up with all of them. The medical research and scientific research communities have known for years that thimerosal in amounts even less than what's allowed in vaccines is a neurotoxin and they know that some children cannot metabolize and excrete thimerosal and they've proven this. The understanding that vaccines cause neurological disorders, permanent brain damage and symptoms of Autistic Spectrum Disorder is known. Maybe not known to you, but you might not be reading peer reviewed reports every day. Most people don't.

      ReplyDelete
    10. Where are your peer reviewed references for each of your statements?

      ReplyDelete